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Erythromycin Raw Material Wholesale Cas 114-07-8

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Erythromycin Raw Material Wholesale Cas 114-07-8

Name:  Erythromycin          

CAS No.:  114-07-8  

Appearance: white or milky white crystal or powder

Molecular formula: C37H67NO13

Molecular Weight:  733.9268

Density: 1.2g/cm3

Melting point: 138-140℃

Boiling point: 818.4°C at 760 mmHg

Flash point: 448.8°C

Vapor pressure: 4.94E-31mmHg at 25°C

  • Product Details

Name:  Erythromycin          

CAS No.:  114-07-8  

Appearance: white or milky white crystal or powder

Molecular formula:C37H67NO13

Molecular Weight:  733.9268

Density: 1.2g/cm3

Melting point: 138-140℃

Boiling point: 818.4°C at 760 mmHg

Flash point: 448.8°C

Vapor pressure: 4.94E-31mmHg at 25°C


Description:

Erythromycin CAS NO.114-07-8 is a macrolide antibiotic. It is a white or light yellow-white crystalline powder. It is odorless and bitter. It is hygroscopic in the air. It is easily soluble in ethanol, chloroform, acetone and ether. It is slightly soluble in water. . The solubility increases after salt formation. It is relatively stable in a dry state, and the aqueous solution is relatively stable under refrigeration, and the potency gradually decreases at room temperature. It is unstable when exposed to acid, and is relatively stable when slightly alkaline, and its potency is significantly reduced below pH4. MP 135-140°C (decomposition), specific rotation -70~78°(2%, ethanol solution).

 

Application:

Erythromycin CAS NO.114-07-8 is a macrolide antibiotic. Its antibacterial spectrum is similar to that of penicillin. It is resistant to Gram-positive bacteria, such as Staphylococcus, Streptococcus pyogenes, Streptococcus viridans, Streptococcus pneumoniae, Streptococcus faecalis, Streptococcus hemolyticus, and Clostridium. Bacillus sp It also has a certain inhibitory effect on Gram-negative bacteria, such as Neisseria gonorrhoeae, Helicobacter, Pertussis, Brucella, Legionella, Meningococcus, Haemophilus influenzae, Bacteroides, some Shigella and Escherichia coli. In addition, it has an inhibitory effect on mycoplasma, actinomycetes, spirochetes, rickettsiae, chlamydia, nocardia, a small number of mycobacteria and amoeba. Staphylococcus aureus and other Staphylococcus and Streptococcus bacteria are easily resistant to this product. It is characterized by strains that are resistant to penicillin and are sensitive to the product.


Specification:

Tests items

Acceptance criteria

Results

Appearance

White or slightly yellow powder or colorless or slightly yellow crystals

White powder

IR Identification

Infrared spectrum is concordant with that of the reference standard

Conforms

Related substances

Impurity A

Not more than 2.0%

0.66%

Impurity B

Not more than 2.0%

0.63%

Impurity C

Not more than 3.0%

0.90%

Impurity D

Not more than 1.0%

0.17%

Impurity E

Not more than 1.0%

0.02%

Impurity F

Not more than 1.0%

0.001%

Impurity H

Not more than 1.0%

0.007%

Impurity L

Not more than 0.4%

0.009%

Impurity M

Not more than 1.0%

0.08%

Any other impurity

Not more than 0.4%

0.10%

Total impurities

Not more than 7.0%

2.5%

Thiocyanate

Not more than 0.3%

0.02%

Water

Not more than 6.5%

0.5%

Sulfated ash

Not more than 0.2%

0.03%

Assay (On anhydrous substance)

Erythromycin B

Not more than 5.0%

0.34%

Erythromycin C

Not more than 5.0%

0.91%

Erythromycin (A+B+C)

93.0%~102.0%

97.2%

Residual Solvent: Methylene chloride

Not more than 600ppm

NDppm

Microbial Limit

Total Aerobic Microbial Count

Not more than cfu103/g

-CFU/g

Total Yeast/Mold Count

Not more than cfu102/g

- CFU/g


Package:

Erythromycin Cas 114-07-8

Erythromycin Cas 114-07-8

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