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Name: Chlorotrimethylsilane CAS number: 75-77-4 Molecular formula: C3H9ClSi Molecular weight: 108.64 EINECS number: 200-900-5 Mol file: 75-77-4.mol
Name: Ethoxytrimethylsilane CAS number: 1825-62-3 Molecular formula: C5H14OSi Molecular weight: 118.25 EINECS number: 217-370-6 Mol file: 1825-62-3.mol
Specification English name: Dimethyldimethoxysilane CAS number: 1112-39-6 Molecular formula: C4H12O2Si Molecular weight: 120.22 EINECS number: 214 189 4 Mol file: 1112-39-6.mol Applications As a structural control agent, chain extender, and filler treatment agent, it is widely used in the treatment of organic silica gel and white carbon black Purpose As a structural control agent, chain extender, and filler treatment agent, it is widely used in the treatment of organic silica gel and white carbon black. This product is used as a structural control agent and chain extender to improve mechanical processing performance, extend the storage time of rubber blends, and can replace hydroxyl silicone oil for use. Widely used in the treatment of organic silicone and white carbon black Purpose Dimethyldimethoxysilane is used as a structural control agent and chain extender to improve mechanical processing performance, extend the storage time of rubber blends, and can replace hydroxy silicone oil....
Properties of trimethyliodosilane Melting point<0 ° C Boiling point 106 ° C (lit.) Density 1.406 g/mL at 25 ° C (lit.) Refractive index n20/D 1.471 (lit.) Flash point − 25 ° F Storage conditions -20 ° C Solubility Reacts Form Liquid Specific gravity 1.47 Clear colors to reddish Water solubility reactions Sensitivity: Moisture&Light Sensitivity Hydrolysis sensitivity 8: Reacts quickly with moisture, water, protoc solvents BRN 1731136 Stability Sensitivity (Reactive) InchiKey CSRZQMIRAZTJOY-UHFFFFAOYSA-N CAS Database 16029-98-4 (CAS DataBase Reference) NIST Chemical Information Iodotrimethylsilane (16029-98-4) EPA Chemical Information Silane, iodotrimethyl - (16029-98-4)
Properties of Hexamethyldisilane Melting point 9-12 ° C (lit.) Boiling point 112-114 ° C (lit.) Density 0.715 g/mL at 25 ° C (lit.) Refractive index n20/D 1.422 (lit.) Flash point 29 ° F Storage conditions Store at<=20 ° C Sol common organic solvents; Insul H2O Form liquid Specific gravity 0.729 Colorless Insoluble in water Double in alcohol, ether and acetone Hydrolysis sensitivity 1: no significant reaction with acute systems BRN 1633463 Stability InchiKey NEXSMEBSBIABKL-UHFFFAOYSA-N CAS Database 1450-14-2 (CAS DataBase Reference) NIST Chemical Substance Information Disilane, hexagonal - (1450-14-2) EPA Chemical Substance Information Disilane, hexagonal - (1450-14-2)
Introduction: Hexamethyldisiloxane (silicone ether, MM sealing agent) is a colorless and transparent liquid that is prone to deliquescence. Insoluble in water, soluble in various organic solvents. Used as silicone oil, silicone rubber, pharmaceuticals, gas chromatography stationary liquids, analytical reagents, hydrophobic agents, etc. Obtained by hydrolysis of trimethylchlorosilane. The physical properties of hexamethyldisiloxane colorless and transparent liquids. Easily deliquescent, flammable, and in contact with high heat, open flames, and strong oxidizing agents, there is a risk of combustion. Boiling point 99.5 ℃. Flash point -1.1 ℃. Relative density (d2525) 0.7606. The refractive index is 1.3750. Insoluble in water, soluble in various organic solvents. Hexamethyldisiloxane is an important primary organic silicon raw material, often used as a capping agent in the production of silicone oil, or as a cleaning agent for silicone rubber, pharmaceuticals, gas c...
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Indroduce
It is suitable for symptomatic treatment of pain, swelling, soft tissue inflammation, traumatic pain and post-operative pain in rheumatoid arthritis and osteoarthritis.
Clinical application
1. oral administration
(1) Osteoarthritis 7.5 mg a day, one-time use, the maximum dose of 15 mg a day;
(2) Ankylosing spondylitis and rheumatoid arthritis 15 mg a day, twice a day, can also be reduced to 7.5 mg a day. The maximum daily dose for adults was 15 mg and that for the elderly was 7.5 mg.
2. Rectal administration
(1) Osteoarthritis, 7.5-15 mg, was inserted into the anus before bedtime;
(2) Ankylosing spondylitis and rheumatoid arthritis, 15 mg or 7.5 mg, were inserted into the anus before bedtime. The elderly 7.5 mg, before going to bed into the anus.
3. Other
Children under the age of 15 are not recommended.
Adverse reactions
Including gastrointestinal reactions (common dyspepsia, nausea, abdominal pain or diarrhea; rare ulcers, bleeding or perforation); anemia, leukopenia or thrombocytopenia, itching, rash; stomatitis; mild dizziness, headache; edema, elevated blood pressure, etc. Common elevated liver enzymes (10%) and occasional renal damage (0.4%). Most disappear after stopping the drug.
Medication contraindication
The following conditions are forbidden: patients with asthma, nasal polyps, angioneurotic edema or urticaria after the use of aspirin or other non-steroidal anti-inflammatory drugs; patients with active peptic ulcer, severe hepatic insufficiency, severe renal insufficiency in non-dialysis patients; patients with gastrointestinal hemorrhage, cerebral hemorrhage or other hemorrhage; patients with severe uncontrolled heart failure; children and years Teenagers under 15 years of age, pregnant women or breastfeeders.
Drug Interaction
1. Combination with methotrexate can increase the blood toxicity of methotrexate.
2. Combination of oral anticoagulant and thrombolytic agents may increase bleeding.
3. It can reduce the antihypertensive and diuretic effects of beta-adrenergic receptor blockers, angiotensin-converting enzyme inhibitors, loop diuretics (except furosemide), thiazide drugs.
4. Combined with potassium-preserving diuretics to reduce diuresis may lead to hyperkalemia or toxic kidney damage.
5. When combined with cyclosporine, the risk of cyclosporine poisoning increased.
6. When combined with levofloxacin and ofloxacin, the risk of seizures increased.
Note: The above contents are only for introduction. Drug use must be carried out under the guidance of doctors in regular hospitals.
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