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Acetamiprid is one of the safety Insecticide for agriculture
2018-10-25 18:25:53
Insecticide acetamiprid is an organic compound with the chemical formula C10H11ClN4. It is an odorless neonicotinoid insecticide produced under the trade names Assail, and Chipco by Aventis CropSciences. It is systemic and intended to control sucking insects (Lepidoptera, Thysanoptera, Hemiptera, mainly aphids) on crops such as leafy vegetables, citrus fruits, pome fruits, grapes, cotton, cole crops, and ornamental plants. It is also a key pesticide in commercial cherry farming due to its effectiveness against the larvae of the cherry fruit fly.
Insecticide acetamiprid is an insecticide belonging to the chloropyridinyl neonicotinoids, this family of insecticides was introduced in the early 1990s. This compound is an insecticide that is introduced for controlling pests, but also for domestic use to control fleas on cats and dogs.
Mechanism of action:
Insecticide acetamiprid is a nicotine-like substance and reacts to the body in a similar way as nicotine. Nicotine is a natural insecticide of which many man-made insecticides are derivatives. Acetamiprid is a nicotinic agonist that reacts with nicotinic acetylcholine receptors (nACh-R). These receptors are located in the post-synaptic dendrites of all neurons in the brain, spinal cord, ganglia and muscular junctions.The activation of the nACh-R receptors causes hyperactivity and muscle spasms, and eventually death. Acetamiprid is highly toxic to insects, but less to mammals. This is probably due to a different form of receptor in vertebrates.
Acetamiprid is used to produce a variety of crops, plants and flowers. It can be used combined with another pesticide with a different mode of action. This way the developing of resistance by pest species can be prevented. According to the US EPA acetamiprid could play a role in battling resistance in the species: Bemisia, greenhouse whiteflies and western flower thrips.
Neonicotinoids act as agonists for nAChR and are selectively toxic to insects versus mammals, because of a higher potency on insect than mammalian nAChRs. This increases their suitability as pesticides.
Safely Indications:

Acetamiprid is classified as unlikely to be a human carcinogen. Acetamiprid has a low acute and chronic toxicity in mammals with no evidence of carcinogenicity, neurotoxicity or mutagenicity. It is classified as toxicity category rating II in acute oral studies with rats, toxicity category III in acute dermal and inhalation studies with rats, and toxicity category IV in primary eye and skin irritation studies with rabbits. It is mobile in soil, but degrades rapidly via aerobic soil metabolism, with studies showing its half life between <1 and 8.2 days. The U.S. Environmental Protection Agency (EPA) does not consider it to be environmentally persistent.

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